Figure 2

Western blot results of fibrotic and anti-fibrotic biomarkers in ischemic muscle by day 14 after critical limb ischemia (CLI) procedure (n = 9). A & B) protein expressions of transforming growth factor (TGF)-β and phosporylated-Smad3. * vs. other groups with different symbols, p < 0.002. C & D) protein expressions of bone morphogenic protein (BMP)-2 and phosporylated-Smad1/5. * vs. other groups with different symbols, p < 0.003. Statistical analysis by ANOVA followed by Bonferroni multiple comparison post hoc test.