Table 7 Percentage change of lipids according to SLCO1B1 haplotypes after 12 months of raloxifene treatment in 53 postmenopausal women
Haplotype | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
*1b | *15 | *1a | |||||||||
Number of copies of haplotype | 0 | 1 | 2 | p value (ANOVA) | 0 | 1 | p value (t-test) | 0 | 1 | 2 | p value (ANOVA) |
Δ HOL (%) | −0.8 (2.9) | −4.8 (2.2) | −10.2 (3.0) | 0.228 | −3.9 (1.8) | −2.8 (3.7) | 0.747 | −6.9 (2.0) | −3.8 (2.7) | 0.3 (2.6) | 0.363 |
Δ HDL (%) | −0.7 (2.9) | 3.8 (3.2) | −9.7 (5.3) | 0.149 | 0.5 (2.4) | 0.3 (4.0) | 0.963 | −3.9 (4.0) | 2.7 (3.1) | −1.0 (3.0) | 0.416 |
Δ LDL (%) | −0.05 (4.01) | −7.8 (2.7) | −13.0 (5.8) | 0.140 | −4.8 (2.5) | −5.2 (5.0) | 0.935 | −10.3 (3.4) | −5.9 (3.4) | 3.0 (4.1) | 0.140 |
Δ TG (%) | 8.7 (7.7) | −1.0 (6.4) | 7.8 (20.7) | 0.626 | −0.7 (6.0) | 14.5 (7.7) | 0.145 | 21.3 (12.1) | −5.9 (4.2) | 12.7 (14.0) | 0.051 |