Augmentation of hepatic microenvironment. (A) SNP-MSCs resulted in the decreased expression of fibrotic marker (α-SMA), Collagen1 (D) and iNOS (F) and increased expression of hepatic markers cytokeratin-18 (B), albumin (C) and eNOS (E) in 1 = Vehicle, 2 = CCl4, 3 = MSCs, 4 = SNP, 5 = SNP-MSCs). G) Quantification of α-SMA, Collagen1, cytokeratin18, albumin, eNOS and iNOS in all treatment groups. All values are expressed as mean ± SEM. P-value < 0.05 was considered significant. *P < 0.05 for SNP-MSCs vs. CCl4; #P < 0.05 for SNP-MSCs vs. MSCs; φP < 0.05 for SNP-MSCs vs. SNP.