Figure 7

The effect of CXCL12 on proliferation in pancreatic cancer cells. A quantitative ATP-based proliferation assay was performed on PANC-1 cells a) treated with CXCL12 and CXCL11 for 72 h.. b) PANC-1 and c) FG cells were transfected with control, CXCR4, or CXCR7 siRNA (100 nM) prior to 72 h of exposure with CXCL12 (200 ng/ml). Proliferation levels presented were normalized to each untreated baseline level, relative increases are depicted. The mean absorbance ± one SD was plotted for each treatment group. * designates p < 0.05.