Figure 1

CXCR4 and CXCR7 expression in human formalin-fixed paraffin-embedded pancreatic cancer specimens. Pancreatic cancer tissue was obtained from patients who had undergone resection for pancreatic adenocarcinoma with Institutional Review Board approval. Tissue blocks were sectioned (5 μm) and deparaffinized with xylene. Antigen retrieval was performed and one section was incubated with the anti-CXCR4 antibody and the next consecutive section from the same tissue block was incubated with the anti-CXCR7 antibody.