Table 1 Clinical and demographic characteristics of patients

Used in real-time PCR and western blot analysis

Number of patients

20

20

20

Age (months)

24.6 ± 8.30

21.4 ± 13.4

22.4 ± 7.67

ns

Body weight (kg)

12.1 ± 2.48

11.1 ± 3.59

11.1 ± 1.89

ns

Sex (female/male)

10/10

11/9

12/8

ns

Peak systolic pressure gradient across the pulmonary valve (mmHg)*

6.5 ± 3.09

78.8 ± 40.51

86.2 ± 14.75

<0.001 vs C group

O ₂ (% saturation)*

98.4 ± 1.15

98.3 ± 1.59

81.5 ± 5.49

<0.001 vs HH group

Used for cell size and IF analysis

Number of patients

5

5

5

Age (months)

17.8 ± 5.97

17.4 ± 5.81

19.0 ± 5.70

ns

Body weight (kg)

11.0 ± 2.21

9.6 ± 1.88

11.7 ± 1.17

ns

Sex (female/male)

2/3

3/2

2/3

ns

Peak systolic pressure gradient across the pulmonary valve (mmHg)*

8.2 ± 3.28

61.4 ± 9.94

79.2 ± 11.03

<0.001 vs C group

O ₂ (% saturation)*

98.5 ± 0.87

97.8 ± 1.10

82.3 ± 5.94

<0.01 vs HH group