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Table 1 Baseline demographics of GERA and PEAR clinical cohorts

From: Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide

 

GERA

PEAR

HCTZ

PEAR

ATEN

HTNDB AA Normotensives

EPS AA Population

N

583

297

374

121

88

Age (y)

48.2 ± 6.7

50.3 ± 8.9

48.6 ± 9.2

45.1 ± 7.1

22.7 ± 5.1

Sex (% female)

47.2

51.2

57.7

52.9

51.1

Race (%)

     

Caucasian

50.3

57.1

58.9

0

0

African-American

49.7

42.9

41.1

100

100

BMI (kg/m2)

31.3 ± 6.0

30.8 ± 5.6

31.0 ± 6.2

30.1 ± 6.8

25.2 ± 4.3

Mean Clinic BP

     

Systolic (mmHg)

146.0 ± 14.4

152.6 ± 13.0

151.4 ± 12.4

118.3 ± 9.1

122.5 ± 8.9

Diastolic (mmHg)

96.1 ± 5.4

98.7 ± 6.1

98.3 ± 6.2

76.7 ± 6.3

68.4 ± 5.9

Mean Home BP

     

Systolic (mmHg)

N/A

146.7 ± 11.2

145.2 ± 9.8

N/A

N/A

Diastolic (mmHg)

N/A

94.3 ± 6.2

93.5 ± 6.0

N/A

N/A

  1. Values are listed as mean ± SD