Skip to main content

Advertisement

Table 1 Baseline demographics of GERA and PEAR clinical cohorts

From: Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide

  GERA PEAR HCTZ PEAR ATEN HTNDB AA Normotensives EPS AA Population
N 583 297 374 121 88
Age (y) 48.2 ± 6.7 50.3 ± 8.9 48.6 ± 9.2 45.1 ± 7.1 22.7 ± 5.1
Sex (% female) 47.2 51.2 57.7 52.9 51.1
Race (%)      
Caucasian 50.3 57.1 58.9 0 0
African-American 49.7 42.9 41.1 100 100
BMI (kg/m2) 31.3 ± 6.0 30.8 ± 5.6 31.0 ± 6.2 30.1 ± 6.8 25.2 ± 4.3
Mean Clinic BP      
Systolic (mmHg) 146.0 ± 14.4 152.6 ± 13.0 151.4 ± 12.4 118.3 ± 9.1 122.5 ± 8.9
Diastolic (mmHg) 96.1 ± 5.4 98.7 ± 6.1 98.3 ± 6.2 76.7 ± 6.3 68.4 ± 5.9
Mean Home BP      
Systolic (mmHg) N/A 146.7 ± 11.2 145.2 ± 9.8 N/A N/A
Diastolic (mmHg) N/A 94.3 ± 6.2 93.5 ± 6.0 N/A N/A
  1. Values are listed as mean ± SD