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Table 2 Blood Pressure Responses to Monotherapy by Measurement Method

From: Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response

  All N = 595 Atenolol N = 293 Hydrochlorothiazide N = 302
Systolic BP Response, mmHg    
Office -13.4 ± 14.7 -13.5 ± 15.6 -13.2 ± 13.7
Home -8.8 ± 9.8 -8.3 ± 10.4 -9.4 ± 9.1
Ambulatory daytime -11.5 ± 10.5 -12.2 ± 11.1 -10.8 ± 9.8
Ambulatory nighttime -9.7 ± 12.5 -8.9 ± 12.9 -10.6 ± 12.1
Contrast P value < 0.001 < 0.001 < 0.001
Diastolic BP Response, mmHg    
Office -8.6 ± 8.9 -10.5 ± 9.4 -6.8 ± 7.9
Home -6.6 ± 6.5 -7.8 ± 6.8 -5.3 ± 6.0
Ambulatory daytime -7.6 ± 7.6 -9.2 ± 7.9 -6.1 ± 7.0
Ambulatory nighttime -6.8 ± 9.5 -7.0 ± 10.0 -6.5 ± 9.0
Contrast P value < 0.001 < 0.001 0.10
  1. BP, blood pressure.