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Table 2 Blood Pressure Responses to Monotherapy by Measurement Method

From: Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response

 

All N = 595

Atenolol N = 293

Hydrochlorothiazide N = 302

Systolic BP Response, mmHg

   

Office

-13.4 ± 14.7

-13.5 ± 15.6

-13.2 ± 13.7

Home

-8.8 ± 9.8

-8.3 ± 10.4

-9.4 ± 9.1

Ambulatory daytime

-11.5 ± 10.5

-12.2 ± 11.1

-10.8 ± 9.8

Ambulatory nighttime

-9.7 ± 12.5

-8.9 ± 12.9

-10.6 ± 12.1

Contrast P value

< 0.001

< 0.001

< 0.001

Diastolic BP Response, mmHg

   

Office

-8.6 ± 8.9

-10.5 ± 9.4

-6.8 ± 7.9

Home

-6.6 ± 6.5

-7.8 ± 6.8

-5.3 ± 6.0

Ambulatory daytime

-7.6 ± 7.6

-9.2 ± 7.9

-6.1 ± 7.0

Ambulatory nighttime

-6.8 ± 9.5

-7.0 ± 10.0

-6.5 ± 9.0

Contrast P value

< 0.001

< 0.001

0.10

  1. BP, blood pressure.