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Figure 1 | Journal of Translational Medicine

Figure 1

From: Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo

Figure 1

Elevated expression of PLSCR1 in CRC cell lines and various human cancer cells. (A) Western blot analysis of lysates from ten different cell lines including eight CRC cell lines (CoLo205, HCT116, SW620, LoVo, HCT15, SW480, WiDr, HT29), HepG2 cells (positive control), and one noncancer cell line (WI-38 fibroblasts). The top and bottom blots show PLSCR1 and actin (loading control). (B) Tissue microarray analysis of PLSCR1 in multiple normal and tumor tissues. Selected images of colon, esophagus, uterus, and thyroid tissues in tissue arrays representing immunohistochemical staining of PLSCR1 are shown. The boxed areas indicated in the left panels (original magnification, ×10) are enlarged and shown in the right panels (original magnification, ×50).

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