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Table 2 Hematologic and biochemical studies among the four groups

From: Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation

Variables SP CLP CLP + H-ADMSC CLP + A-ADMSC p-value
At 24 hour      
 AST 57 ± 7.1a 153.7 ± 14.1b 160.9 ± 27.5b 126.1 ± 20.9c <0.001
 ALT 31.9 ± 6.7 46.1 ± 5.1 46.9 ± 18.8 35.3 ± 11.5 0.06
 BUN 20.3 ± 2.4 21.8 ± 6.9 22.1 ± 6.3 23.4 ± 9.3 0.849
 Creatinine 0.51 ± 0.12 0.77 ± 0.15 0.74 ± 0.25 0.66 ± 0.14 0.051
 WBC count 8.1 ± 2.0 4.9 ± 2.6 7.7 ± 2.5 6.8 ± 1.4 0.057
At 72 hour      
 AST 46.1 ± 11.1a 106.6 ± 12.4b 134 ± 23.4c 81.6 ± 17.1d <0.001
 ALT 25 ± 5.1 34.6 ± 10.1 36 ± 7.6 24.7 ± 14 0.06
 BUN 16.7 ± 1.9a 28.8 ± 6.5b 28.3 ± 14.2b 25 ± 5.9b 0.018
 Creatinine 0.5 ± 0.07a 0.78 ± 0.14b 0.83 ± 0.17b 0.61 ± 0.11a <0.001
 WBC count 7.7 ± 1.9a 12.6 ± 2.8b 9.2 ± 3.1c 9.5 ± 2.3c 0.016
  1. Data are expressed as means ± SD.
  2. AST = aspartate aminotransferase; ALT = alanine aminotransferase; BUN = blood urea nitrogen; WBC = white blood cell count.
  3. SP = sham procedure; CLP = cecal ligation and puncture; H-ADMSC = healthy adipose-derived mesenchymal stem cells; A-ADMSCs = apoptotic adipose-derived mesenchymal stem cells.