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Figure 4 | Journal of Translational Medicine

Figure 4

From: Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation

Figure 4

Circulating and splenic levels of T lymphocytes at 72 h after CLP / SP . A) Circulating levels of CD3+/CD4+ cells (helper T cells). * vs. other bars with different symbols, p < 0.001. B) Splenic levels of CD3+/CD4+ cells. * vs. other bars with different symbols, p < 0.001. C) Circulating levels of CD3+/CD8+ cells (cytotoxic T cells). * vs. other bars with different symbols, p < 0.001. D) Splenic levels of CD3+/CD8+ cells. * vs. other bars with different symbols, p < 0.001. E) Circulating levels of CD4 + CD25 + Foxp3+ cells (Treg cells). * vs. other bars with different symbols, p < 0.001. F) Splenic levels of Treg cells. * vs. other bars with different symbols, p < 0.001. All statistical analyses used one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡, §) indicating significance (at 0.05 level). CLP = cecal ligation and puncture; Normal indicates sham procedure; H-ADMSCs = healthy adipose-derived mesenchymal stem cells; A-ADMSCs = apoptotic adipose-derived mesenchymal stem cells.

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