Overexpression of the secretory small GTPase Rab27B in human breast cancer correlates closely with lymph node metastasis and predicts poor prognosis

Table 3 Relationship between Rab27B expression level and clinicopathologic parameters of BC

Variable	Number of cases	Rab27B expression		P value
		High expression	Low expression
Age (years)
≥ 47^a	103	46(44.7%)	57(55.3%)
< 47	118	61(51.7%)	57(48.3%)	0.297
Pathologic grade
I	47	15(31.9%)	32(69.1%)
IIIII	174	92(52.9%)	82(47.1%)	0.011*
Clinical stage
III	181	80(44.2%)	101(55.8%)
III	40	27(67.5%)	13(32.5%)	0.008*
Tumor size stage
T1	63	32(50.8%)	31(49.2%)
T2 + T3	158	82(51.9%)	76(48.1%)	0.883
Menopausal status
Absent	90	53(58.9%)	37(41.1%)
Present	131	61(46.6%)	70(53.4%)	0.072
Lymph node metastasis
Metastasis	116	65(56.0%)	51(44.0%)
No metastasis	105	42(40.0%)	63(60.0%)	0.021*
ER status
Negative	97	37(38.1%)	60(61.9%)
Positive	124	70(56.5%)	54(43.5%)	0.007*
PR status
Negative	91	39(42.9%)	52(57.1%)
Positive	130	68(52.3%)	62(47.7%)	0.166
CerbB2 status
0,1+,2+	147	74(50.3%)	73(49.7%)
3+	74	33(44.6%)	41(55.4%)	0.42
Living status
Live	170	63(37.1%)	107(62.9%)
Dead	51	44(86.3%)	7(13.7%)	<0.001*

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