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Table 2 Comparison of proposed QL-MI assay with hs-ELISA and nephelometry

From: Sensitive and rapid quantification of C-reactive protein using quantum dot-labeled microplate immunoassay

  QL-MI (One-step format) QL-MI (Two-step format) hs-ELISA[12, 13] Nephelometrya
Sensitivity 0.21 μg/L 0.06 μg/L 0.039 μg/L 1000 μg/L
Intra-day precision(CV) < 2.17% < 1.75% 2.4-10.4% 2.6-11.1%
Inter-day precision(CV) < 9.52% < 2.27% 1.7-17.6% 4-12.1%
Linearity 0.001-100 mg/L 0.001-100 mg/L 10-5-0.02 mg/L 1-960 mg/L
Detection time 1 hour 1.5 hours 2-6 hours 40 minutes
  1. aData are from the instruction of CRP detection reagent from Beckman Coulter