Table 4 Summary of tremelimumab pharmacokinetic parameter values following a 1-hour intravenous infusion in comparison with those following a 5 -hour intravenous infusion in A3671008 Study
| Â | A3671022 Study | A3671008 Study | ||||
|---|---|---|---|---|---|---|
|  | Cmax | AUCinf (μg*h/mL) | t1/2 | Cmax | AUCinf (μg*h/mL) | t1/2 |
|  | (μg/mL) |  | (days) | (μg/mL) |  | (days) |
N | 42 | 32 | 32 | 150 | 150 | 150 |
Mean | 322 | 104500 | 19.6 | 329 | 112719 | 19.2 |
SD | 62 | 32400 | 5.7 | 112 | 40933 | 5.9 |