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Table 3 Allelic frequency (A) and frequency of homozygous variant patients (B) for prothrombotic gene variants in AMI female, male and general population

From: Prothrombotic gene variants as risk factors of acute myocardial infarction in young women

Group A FV Leiden FII G20210A MTHFR C677T Beta Fibrinogen -455G>A
Female 17/490 (3.5) 16/472 (3.4) 220/466 (47.2) 93/470 (19.8)
Male 23/906 (2.5) 25/878 (2.8) 561/880 (63.7)* 141/890 (15.8)
General population B 42/1718 (2.4) 43/1718 (2.5) 760/1818 (41.8) 186/1308 (14.2)
Female 0 0 61/233 (26.2) 17/235 (7.2)
Male 0 0 175/440 (39.8)** 27/445 (6.1)
General population 0 0 162/909 (17.8) 18/654 (2.75)
  1. *Significantly different (p<0.001) versus the general population (O.R.: 2.45; C.I.: 2.07-2.89).
  2. ** Significantly different (p<0.001) versus the general population (O.R.: 3.05; C.I.: 2.36-3.93).