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Table 1 Reported adverse effect during IGF-I treatment

From: Human conditions of insulin-like growth factor-I (IGF-I) deficiency

Adverse effect IGF-I doses (μg/Kg/day) References
Tachycardia 150-200 [397]
120-180 [398]
Hypoglycemia 60-120 [377, 380]
80-120 [378, 387]
Intracrenial pressure increment 80-120 [378, 387]
Lipohypertrophy 60-120 [377, 387]
Tonsillar/adenoidal hypertrophy 60-120 [377, 387]
Headache and vomiting 80-120 [387]
Facial edema 120-180 [398]
120 [373]
Asthenia, orthostatic hypotension 120 [373]
Arthralgia/myalgia 120 [373]
  1. Subcutaneously, daily, for at least 1 year.