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Figure 8 | Journal of Translational Medicine

Figure 8

From: A gender-related action of IFNbeta-therapy was found in multiple sclerosis

Figure 8

Gender specific biomarkers for homeostasis in immunological, neurological and therapeutic pathways. Re-establishment of immunological and neurological homeostasis in treated patients induced by gender specific cytokine pathways, re-establishes the above relationships between the production of IL6 and IL4 (from negative, the condition of untreated patients, to positive, the condition of healthy subjects) in men; similarly in women homeostasis is re-established when the relationship between the production of IL6 and IL10 reverses (from positive, the condition of untreated patients, to negative, the condition of healthy subjects). Additionally, the significance of sCD30 and TGFβ as a dual clinical biomarker was confirmed for both sexes and gender specific new clinical biomarkers were identified.

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