Figure 6

APC analysis in MS treated patients using IDC, DC and whole blood Th-cytokine data-driven computational models of disease state. Re-establishment of IL6 immunological pathways are responsible for the re-establishment of neurological (no increase of EDSS) and immunological (Th cell-network) homeostasis in treated patients and is induced by gender specific cytokine pathways. In fact , the IL6 vector in women, and the IFNγ vector in men, negatively opposed their respective EDSS vectors and the relationships between the production of IL6, IL4 and IL6, IL10 reverses to that found in healthy subjects, in both sexes.