Figure 11

Flow cytometric analysis of FUS exposure region. Flow-cytometric analysis of the ratios of two TIL subtypes at different time points (1, 3, and 18 days after FUS exposure), for the untreated control group (Cont., white bars; defined as animals without MB-presented FUS exposure) compared to the MB-enhanced 1.4-MPa FUS treated group (Exp., black bars). (A) Ratio of CD8 and CD4⁺Foxp3⁺ TILs; (B) ratio of CD8 and CD117⁺FceRIa⁺/CD45⁺ TILs (mast cells); (C) ratio of CD4⁺Foxp3- and CD4⁺Foxp3⁺ TILs; (D) ratio of CD8 and CD4⁺Foxp3- TILs. FUS exposure was set to 1.4-MPa of pressure, in the presence of microbubbles. (* indicates p < 0.05; ** indicates p < 0.005).