Table 3 Final set of derived proteins representing candidate biomarker of AD
From: Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation
STANDARD PROTEIN SYMBOL | COMMON ALIASES | |
|---|---|---|
Alpha 1-antichymotrypsin | SERPINA3 | serpin peptidase inhibitor clade A, AACT, ACT |
Amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease amyloid protein) | APP | AD1 (Alzheimer disease), ABETA (amyloid beta A4 protein) |
Apolipoprotein D | APOD | |
Apolipoprotein E | apoE | AD2 (Alzheimer disease 2) |
B-cell leukemia/lymphoma 2 | BCL2 | |
Beta-site APP-Cleaving Enzyme 1 | BACE1 | |
Butyrylcholinesterase | BCHE | |
C-reactive protein, pentraxin-related | CRP | |
Choline Acetyltransferase | CHAT | CHOACTase |
Clusterin | CLU | APOJ (Apolipoprotein J) |
Complement component 1, q subcomponent, beta polypeptide | C1QB | |
Estrogen Receptor 1 (alpha) | ESR1 | |
Glial fibrillary acidic protein | GFAP | |
Heat shock 70kD protein 5 (glucose-regulated protein) | HSPA5 | |
Interleukin 1 beta | IL1B | |
Interleukin 6 | IL6 | IFNB2 (Interferon beta-2) |
Matrix Metallopeptidase 9 | MMP9 | CLG4B (92 kDa gelatinase, 92 kDa type IV collagenase) |
Nerve Growth Factor | NGF | NGFB |
Nitric Oxide Synthase 2A | NOS2 | NOS2A, INOS (Inducible NOS), HEP-NOS (Hepatocyte NOS) |
PRKC, apoptosis, WT1, regulator | PAWR | PAR4 (Prostate apoptosis response 4 protein) |
Prostaglandin-Endoperoxide Synthase 2 | PTGS2 | PGHS2, COX2 (Cyclooxygenase 2b) |
Transforming Growth Factor, Beta 1 | TGFB1 | |
Transthyretin | TTR | |
Tumor Necrosis Factor (TNF superfamily, member 2) | TNF | TNFA, TNF-alfa |
Urokinase Plasminogen Activator Receptor | PLAUR | uPAR |