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Table 1 Comparison of immunohistochemical scores across patient groups sorted by histological subtype or clinical / molecular characteristics

From: Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

Compared groups Statistical test used Result
EZH2
PDSS and MPSS and BPSS Kruskal-Wallis P < 0.001
PDSS vs. MPSS Mann–Whitney P < 0.001
PDSS vs. BPSS Mann–Whitney P = 0.001
MPSS vs. BPSS Mann–Whitney NS
H3K27me3
PDSS and MPSS and BPSS Kruskal-Wallis P < 0.001
PDSS vs. MPSS Mann–Whitney P < 0,001
PDSS vs. BPSS   P = 0.001
MPSS vs. BPSS Mann–Whitney NS
Ki-67
PDSS and MPSS and BPSS 1 P < 0.001
PDSS vs. MPSS Mann–Whitney P < 0,001
PDSS vs. BPSS Mann–Whitney NS
Compared groups EZH2 Ki-67 H3K27me3
Gender
Male vs. female NS NS NS
Age
≤25 y/o vs. >25 y/o NS NS NS
Location
Central vs. peripheral NS NS NS
Tumor size
<5cm vs. ≥5cm P < 0.001 NS P = 0.032
Distant metastasis
Present vs. absent P < 0.001 P = 0.021 P = 0.003
Fusion gene
SYT-SSX1 vs. SYT-SSX2 NS NS NS
  1. (PDSS: poorly differentiated synovial sarcoma; MPSS: monophasic synovial sarcoma; BPSS: biphasic synovial sarcoma; NS: not significant).