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Table 1 Comparison of immunohistochemical scores across patient groups sorted by histological subtype or clinical / molecular characteristics

From: Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

Compared groups

Statistical test used

Result

EZH2

PDSS and MPSS and BPSS

Kruskal-Wallis

P < 0.001

PDSS vs. MPSS

Mann–Whitney

P < 0.001

PDSS vs. BPSS

Mann–Whitney

P = 0.001

MPSS vs. BPSS

Mann–Whitney

NS

H3K27me3

PDSS and MPSS and BPSS

Kruskal-Wallis

P < 0.001

PDSS vs. MPSS

Mann–Whitney

P < 0,001

PDSS vs. BPSS

 

P = 0.001

MPSS vs. BPSS

Mann–Whitney

NS

Ki-67

PDSS and MPSS and BPSS

1

P < 0.001

PDSS vs. MPSS

Mann–Whitney

P < 0,001

PDSS vs. BPSS

Mann–Whitney

NS

Compared groups

EZH2

Ki-67

H3K27me3

Gender

Male vs. female

NS

NS

NS

Age

≤25 y/o vs. >25 y/o

NS

NS

NS

Location

Central vs. peripheral

NS

NS

NS

Tumor size

<5cm vs. ≥5cm

P < 0.001

NS

P = 0.032

Distant metastasis

Present vs. absent

P < 0.001

P = 0.021

P = 0.003

Fusion gene

SYT-SSX1 vs. SYT-SSX2

NS

NS

NS

  1. (PDSS: poorly differentiated synovial sarcoma; MPSS: monophasic synovial sarcoma; BPSS: biphasic synovial sarcoma; NS: not significant).
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Journal of Translational Medicine

ISSN: 1479-5876

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