Treatment groups | Nox (6 hrs) | IH (6 cycles) | SH (6 hrs) | P1 | P2 |
|---|
Controls (n=5) | 1.97 ± 0.7 | 0.8 ± 0.5 | 1.05± 0.6 | 0.002†| 0.04 |
Controls* (n=3) | 2.0 ± 0.4 | 1.14 ± 0.4 | ND | 0.09 |  |
Controls pooled (n=8) | 1.99 ± 0.3 | 0.97 ± 0.2 | ND | 0.001 |  |
OSA (n=7) | 1.0 ± 0.5‡ | 0.63 ± 0.3 | ND | 0.09 |  |
- Normoxia (Nox), intermittent hypoxia (IH), sustained hypoxia (SH).
- * - Healthy controls were investigated in parallel with OSA patients in the Sleep Lab.
- ND – not determined. Values represent means ± SD. P1 - statistical significance, IH vs. Normoxia (Nox); P2 - statistical significance, SH vs. Nox. †Once Bonferroni correction was added to compare the effects of IH and SH vs. Nox (for multiple comparisons, values of p<0.017 were considered significant), only the effects of IH remained significant.
- ‡−Differences between OSA patients and controls under normoxic conditions, p=0.015. A paired two-tailed t test was used for a single comparison.
