Drugs | IC502(μM) | Maximum serum level (μM) | Conc3. tested in MCA (μM) | Ratio of tested conc. to IC50 |
---|---|---|---|---|
Bortezomib | 0.34 | 0.31 | 3.4, 0.34, 0.17, 0.03 | 10x, 1x, 0.5x, 0.1x |
Ouabain | 0.08 | 0.13 | 0.8, 0.16, 0.08 | 10x, 2x, 1x |
Methotrexate | 0.02 | 10-100 | 2, 1, 0.2 | 100x, 50x, 10x |
Pyrimethamine | 0.75 | 8.0 | 7.5, 3.7 | 10x, 5x |