Figure 5

Caspase-3 and -7 activity of NCI-H295R treated with bortezomib, ouabain, methotrexate, and pyrimethamine for 48 and 72 hours. The results were shown in the ratios of caspase activity in treated NCI-H295R to corresponding vehicle controls. Caspase activities of treated cells were compared to respective vehicle controls. * p value <0.05 but ≥ 0.01, ** p value < 0.01.