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Figure 4 | Journal of Translational Medicine

Figure 4

From: Four clinically utilized drugs were identified and validated for treatment of adrenocortical cancer using quantitative high-throughput screening

Figure 4

Three-dimensional multicellular aggregates (MCA) of NCI-H295R and SW13 treated with bortezomib (4A), ouabain (4B), methotrexate (4C), and pyrimethamine (4D). Cells treated with bortezomib, ouabain, and methotrexate had noticeably smaller MCAs or disintegration of MCAs. Pyrimethamine treated SW13 cells developed noticeably smaller MCAs. Pyrimethamine had no effect on NCI-H295R MCAs.

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Journal of Translational Medicine

ISSN: 1479-5876

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