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Figure 4 | Journal of Translational Medicine

Figure 4

From: Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis

Figure 4

Biomarkers of type III collagen turnover on day 7 and 22 corrected to baseline. A, B: Type III collagen degradation detected with C3M. Range of measurement was [2.6-35.5]. C, D: Formation of type III collagen detected with P3NP. Range of measurement was [13.9-71.5]. E, F: Calculations of type III collagen turnover Range of measurement was [0.1-0.6]. The CIA group (black, n = 10) and control animals (white, n = 10) were compared by Mann-Whitneyt-test. All statistical analyses were calculated based on baseline corrected values. Data are shown as mean ± SEM and significance levels as *: P < 0.05, **: P < 0.01, ***: P < 0.001.

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