Figure 1
The percentage increase in paw volume (A), paw score (B), percentage disease incidence (C), and percent weight changes (D) observed post 1st immunization. The CIA group (squares, n = 10) and control animals (circles, n = 10) were compared by Mann–Whitney t-test. All statistical analyses were calculated based on baseline corrected values. Data are shown as mean ± SEM and significance levels as *: P < 0.05, **: P < 0.01, ***: P < 0.001.