Step | covariate removed | no. of variables | log-l | AIC | cvlog-l |
---|
0 | all (null model) | 0 | -675.7 | -675.7 | -846.8 |
1 | none (final model) | 6 | -502.1 | -509.1 | -743.1 |
2 | β2M | 5 | -504.6 | -510.6 | -738.8 |
3 | β2M and sex | 4 | -618.9 | -623.9 | -738.8 |
- The final model included the following 6 variables: Binet stage, age > 65 years, unmutated IgVH, presence of del17p, male sex, β2 M > ULN
- Log-l: log-likelihood, AIC: Akaike's information criterion (AIC); cvlog-l: cross-validated log likelihood Removal of the least important variables (beta2M and sex) in step 2 and 3 resulted in a reduction of the fit by at least 2 criteria, demonstrating the validity of the model with 6 variables (according to reference #26)