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Table 3 Prevalence of somatic mutations in PIK3CA gene

From: Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia

Exon

Mutated cases(%)*

Protein

DNA

9

1 (1.5%)

E542K

c.1624 G > A

 

54 (80.6%)

E545A

c.1634A > C

 

4 (6.0%)

E545G

c.1634A > G

 

1 (1.5%)

E545K

c.1633 G > A

20

1 (1.5%)

M1043I

c.3129 G > T

 

6 (8.9%)

H1047R

c.3140A > G

  1. *percentages are referred to the series of 67 positive cases.