Table 3 Multivariate survival analysis of CDKN2A methylation in colorectal cancer
MODEL 1 | MODEL 2 | ||||||
|---|---|---|---|---|---|---|---|
HR (95%CI) | P-value | HR (95%CI) | P-value | ||||
CDKN2A | Negative | 1.0 | 0.0416 | CDKN2A | Negative | 1.0 | 0.0021 |
Methylated | 1.36 (1.1-1.8) | Methylated | 1.66 (1.2-2.3) | ||||
Age | Baseline | 1.0 | MSI | MSS/MSI-L | 1.0 | 0.0273 | |
1-year | 1.04 (1.02-1.05) | <0.0001 | MSI-H | 0.63 (0.4-0.9) | |||
pT | pT1-2 | 1.0 | <0.0001 | BRAF | Wild-type | 1.0 | 0.2165 |
pT3-4 | 1.98 (1.3-2.9) | Mutation | 1.32 (0.9-2.0) | ||||
pN | pN0 | 1.0 | <0.0001 | ||||
pN1-2 | 2.52 (1.9-3.3) | ||||||