Skip to main content

Table 3 Multivariate survival analysis of CDKN2A methylation in colorectal cancer

From: Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing

  MODEL 1   MODEL 2
   HR (95%CI) P-value    HR (95%CI) P-value
CDKN2A Negative 1.0 0.0416 CDKN2A Negative 1.0 0.0021
  Methylated 1.36 (1.1-1.8)    Methylated 1.66 (1.2-2.3)  
Age Baseline 1.0   MSI MSS/MSI-L 1.0 0.0273
  1-year 1.04 (1.02-1.05) <0.0001   MSI-H 0.63 (0.4-0.9)  
pT pT1-2 1.0 <0.0001 BRAF Wild-type 1.0 0.2165
  pT3-4 1.98 (1.3-2.9)    Mutation 1.32 (0.9-2.0)  
pN pN0 1.0 <0.0001     
  pN1-2 2.52 (1.9-3.3)