(Left) Pairwise linkage disequilibrium between IRF5 polymorphisms in tumor infiltrating lymphocytes (TILs). D’ and r2 were calculated using LDPlotter tool. D’ values for linkage disequilibrium among the major alleles of each of IRF5 are shown. IN-DEL = insertion/deletion. (Right) Samples studied: 140 TILs, 112 parental melanoma metastases and 9 cell lines derived from some metastases.