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Table 3 Toxicity

From: Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

 

Grade 1

Grade 2

Grade 3

Grade 4

Performance status

1

4

1

 

Fatigue

2

3

1

 

Leucopenia

   

6

Neutropenia

   

6

Lymphopenia

   

6

Thrombopenia

  

2

1

Anemia

 

6

  

Nausea

1

4

  

Diarrhea

2

2

1

 

Vomiting

2

 

1

 

Infections

2

 

1

 

Alopecia

 

6

  

Dermatitis

2

1

  

Allergic reaction

3

   

Low sodium levels

2

 

3

1

  1. No grade 3–4 events were associated with Interleukin-2 treatment. Grade is referring to Common Terminology Criteria for Adverse Events (CTCAE) v. 3.0. Digits in the table are referring to number of patients with the given adverse event.