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Figure 6 | Journal of Translational Medicine

Figure 6

From: Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells

Figure 6

Separation of tumor-initiating cells from GI-101A upon an EMT induction and the tumorigenicity test. (A) Flow cytometry sorting of tumor-initiating cells from GI-101A upon an EMT induction. CD44+CD24- (P4), CD44+CD24+ (P5) and ESA+ (P6) gates were established based on uninduced cells. (B) Tumor forming capability of CD44+CD24+ESA+ and CD44+CD24-ESA+ cells were assessed in mice by orthotopic implantation.

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