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Table 2 Demographic and clinical characteristics of the study subjects

From: Genetic variation in the TNF receptor-associated factor 6 gene is associated with susceptibility to sepsis-induced acute lung injury

Characteristic

Sepsis alone patients

Sepsis-induced ALI patients

P Value

Total no.

276

272

N.A

Patient age

63.3 ± 13.8

64.1 ± 12.5

0.65

Male patients

163 (59.1%)

167 (61.4%)

0.58

BMI

21.8 ± 5.4

22.1 ± 8.1

0.14

Smoker

115 (41.7%)

113 (41.5%)

0.98

Liver cirrhosis

7 (2.5%)

8 (2.9%)

0.80

Diabetes

37 (13.4%)

32 (11.8%)

0.56

30-d mortality

110 (39.9%)

142 (52.2%)

0.004

APACHE II score

14.7 ± 7.2

19.6 ± 3.4

<0.001

Organ failure

1.9 ± 0.2

3.1 ± 0.2

<0.001

Transfusion of PRBC

75 (27.2%)

105 (38.6%)

0.004

Number of PRBC transfused

1.2

1.6

0.012

Infection site

   

Pulmonary source

158 (57.2%)

179 (65.8%)

0.039

Extrapulmonary source

118 (42.8%)

93 (34.2%)

0.039

  1. ALI, acute lung injury; N.A, not applicable; BMI, body mass index; APACHE II, acute physiology and chronic health evaluation; PRBC, packed red blood cells.