Genetic variation in the TNF receptor-associated factor 6 gene is associated with susceptibility to sepsis-induced acute lung injury

Table 1 Characteristics of the genotyped SNPs in the genes of TLR signaling pathway

Gene	SNP	Location	Major/minor allele	HWEP value
MyD88	rs6853	3′ UTR	A/G	0.35
	rs7744	3′ UTR	A/G	0.48
IRAK1	rs1059703	exon	C/T	0.45
IRAK4	rs3794262	intron	A/T	0.48
	rs4251429	intron	G/C	0.97
	rs4251545	exon	G/A	0.75
	rs4251569	intron	C/T	0.47
	rs4251513	intron	C/G	0.94
	rs4251466	intron	C/T	0.39
	rs4251431	intron	G/T	0.37
	rs1461567	intron	C/T	0.11
TRAF6	rs540386	intron	C/T	1.00
TRAF6	rs4755453	intron	G/C	0.32
	rs5030493	intron	T/A	1.00

SNP, single nucleotide polymorphism; HWE, Hardy-Weinberg equilibrium; UTR, untranslated region.

ISSN: 1479-5876