Figure 6

Western blot results of apoptotic and angiogenic factors in ischemic quadriceps by day 21 following CLI procedure (n = 8). A) protein expression of cleaved (C) poly(ADP-ribose) polymerase (PARP).* vs. other groups with different symbols, p < 0.006. B) protein expression of cleaved casapse 3 (C-Csp-3).* vs. other groups with different symbols, p < 0.004. C) protein expression of endothelial nitric oxide synthase (eNOS).* vs. other groups with different symbols, p < 0.002. Statistical analysis in each group by ANOVA followed by Bonferroni multiple comparison post hoc test. CLI = critical limb ischemia; Cil = cilostazol; Clo = clopidogrel.