Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response

Table 2 Multivariate Analysis of Overall Survival

Term	Risk Ratio	Lower CL	Upper CL	p-value
Age	0.86	0.05	13.57	0.92
Debulking (sub = 0 optimal = 1)	0.36	0.07	1.72	0.19
Drug (non Best = 0 Best = 1)	0.21	0.05	0.65	< 0.01
Ln ca 125	1.18	0.08	19.29	0.90
Size of residual (none = 0 some = 1))	0.59	0.12	2.24	0.45

Cox proportional hazards model for 61 evaluable patients with stage III or IV primary disease. Risk ratios calculated per change in regressor over entire range. Patients (n = 3) with no debulking were omitted. CL, confidence limit of risk ratio.

ISSN: 1479-5876