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Table 1 IC 50 values of P276-00 and gemcitabine in the different pancreatic cancer cell lines

From: Molecular evidence for increased antitumor activity of gemcitabine in combination with a cyclin-dependent kinase inhibitor, P276-00 in pancreatic cancers

Cell line

P276-00 IC50(μM)

Gemcitabine IC50(nM)

AsPC-1

1.58 ± 0.22

190 ± 14.14

BxPC-3

1.6 ± 0.14

80 ± 14.14

Capan-1

1.67 ± 0.12

666.7 ±115.5

MIA PaCa-2

0.83 ± 0.16

733.3 ± 57.7

PANC-1

0.58 ± 0.09

225 ± 31.09