Figure 1

The effect of P276-00 and gemcitabine treatment on growth of five pancreatic cancer cell lines. Cells were seeded in 96-well plates and incubated overnight. P276-00 or gemcitabine was added at the indicated concentrations and cells were further incubated for 48 h. Cell proliferation was determined using PI assay. (A &B) The 50% inhibitory concentration of P276-00 in five different pancreatic cancer cell lines. (C &D) The 50% inhibitory concentration of gemcitabine in five different pancreatic cancer cell lines.