Table 1 Phenotypic analysis of tumor infiltrating iNOS + P1a and negative P4 subpopulations
From: Characterization of iNOS+ Neutrophil-like ring cell in tumor-bearing mice
P4 | P1a | |
|---|---|---|
Monocyte/PMN subset marker/Migration | ||
Ly6C | + | -/+ |
Ly6G | ++ | - |
CXCR2 | ++ | - |
CCR3 | + | - |
Siglec-F | - | -/+ |
F4/80 | - | ++ |
CXCR4 | - | - |
CD62L | - | - |
CD49d | ++ | ++ |
Adhesion/Activation Molecules | ++ | |
CD44 | ++ | ++ |
CD43 | ++ | - |
CD103 | - | - |
CD138 | ++ | ++ |
CD54 (ICAM-1) | ++ | ++ |
Antigen presentation | - | |
MHC I | ++ | - |
MHC II | - | - |
CD86 (B7-2) | + | + |
CD11c | - | - |
Differentiation | - | |
CD119 (IFNGR1) | ++ | - |
CD124 (IL-4Ra) | ++ | + |
CD115 (CSFR1) | - | - |
CD309 (VEGFR2) | + | + |
Potential T-cell suppressive marker | ||
B7H1 (PD-L1) | + | + |
B7DC (PD-L2) | - | - |
FASL | + | - |
Pattern recognition receptor | - | |
CD14 | - | - |
TLR2 | + | + + |