Figure 6
From: Novel HER2 Aptamer Selectively Delivers Cytotoxic Drug to HER2-positive Breast Cancer Cells in Vitro
Evaluation of cellular uptake of Dox. Confocal microscopy images of HER2-positive SK-BR-3 cells and HER2-negative MDA-MB-231 cells treated with free Dox (A&B) or Apt-Dox (C&D). Flow cytometry profiles of HER2-positive SK-BR-3 cells (E) and HER2-negative MDA-MB-231 cells (F) after treatments with free Dox (black lines) or Apt-Dox (grey lines). The filled histograms are the control signals generated by untreated cells.