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Figure 4 | Journal of Translational Medicine

Figure 4

From: Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy

Figure 4

Changes in protein expressions of inflammatory markers in kidney 24 weeks after CKD induction A & B). Remarkably increased protein expressions of NADPH oxidase (NOX)-1 and NOX-2 in groups 2 and 3 than in group 1. Notably higher expressions in group 4 than in groups 1, 2, and 3, but significantly decreased in group 5 compared with group 4. For NOX-1 and NOX-2, *p < 0.001 between indicated groups. C) Notably elevated protein expression of nuclear factor (NF)-κB in group 3 than in groups 1 and 2. Further increase in group 4 compared with in groups 1, 2, and 3, but significantly lower in group 5 than in group 4. *p < 0.002 between indicated groups. D) Significantly higher protein expression of inter-cellular adhesion molecule (ICAM)-1 in groups 2 and 3 than in group 1. Further remarkable increase in group 4 compared with groups 1, 2, and 3, but notably lower in group 5 than in group 4. *p < 0.001 between indicated groups. All statistical analyses using one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡, §) indicate significance (at 0.05 level) (n = 10 in each group).

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