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Figure 3 | Journal of Translational Medicine

Figure 3

From: Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy

Figure 3

Percentage of intact renal tubules in CKD rats. Periodic Acid Schiff (PAS) staining (200 x) of kidney sections in groups 1 to 5 animals (A, B, C, D, E) showing notable renal tubular destruction (yellow arrows) in groups 3 and 4 compared with groups 1 and 2. Remarkable alleviation in renal tubular damage in group 5 compared to groups 3 and 4. Also note the thickened basal membrane (green arrowheads) and dilated Bowman's capsules (black asterisks) and fibrotic changes in interstitial areas of kidney (blue asterisks) in groups 3 and 4 compared with other groups by 24-week after CKD induction. L) * vs. other groups, p < 0.0001 (by one-way ANOVA). Symbols (*, †, ‡, §) indicate significance (at 0.05 level by Bonferroni multiple comparison post hoc test). Scale bars in right lower corner represent 50 μm in A to E (n = 10 in each group).

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