Table 2 The Baseline Characteristics, Laboratory Findings and Echocardiography Results

Initial body weight (g)

26.0 ± 0.72

25.7 ± 0.66

25.7 ± 0.87

0.675

Final body weight (g)

34.4 ± 1.48^a

43.9 ± 1.55^b

35.4 ± 2.21^a

<0.0001

Heart weight (g)

0.14 ± 0.01^a

0.19 ± 0.02^b

0.15 ± 0.02^a

<0.0001

Ratio of heart weight to tibial bone length

0.070 ± 0.001^a

0.095 ± 0.002^b

0.075 ± 0.017^a

<0.001

Abdominal fat weight (g)

1.66 ± 0.41^a

4.09 ± 0.65^b

2.35 ± 0.08^c

<0.0001

Total cholesterol (mg/dl)†

136.3 ± 11.8^a

232.8 ± 7.53^b

188.8 ± 9.45^c

<0.001

Initial fasting blood glucose level (mg/dl)†

98.3 ± 9.0

103 ± 8.6

101.3 ± 9.4

0.688

Final fasting blood glucose level (mg/dl)†

142.5 ± 18.3^a

307.5 ± 74.7^b

181.2 ± 19.7^c

<0.0001

Echocardiograph (baseline)

Thickness of inter-ventricular septum (mm)

0.83 ± 0.09

0.82 ± 0.08

0.818 ± 0.098

0.616

Thickness of posterior wall (mm)

0.76 ± 0.09

0.77 ± 0.11

0.776 ± 0.089

0.720

Left ventricular end-diastolic dimension (mm)

3.93 ± 0.26

4.10 ± 0.10

4.108 ± 0.083

0.117

Left ventricular end-systolic dimension (mm)

2.63 ± 0.23

2.71 ± 0.21

2.69 ± 0.170

0.809

Fractional shortening (%)

34.4 ± 2.01

32.7 ± 1.98

32.98 ± 1.64

0.240

Left ventricular ejection fraction (%)

64.0 ± 2.49

62.5 ± 2.43

62.27 ± 2.04

0.455

Echocardiograph (at end of study period)

Thickness of inter-ventricular septum (mm)

0.86 ± 0.08

0.87 ± 0.06

0.859 ± 0.07

0.789

Thickness of posterior wall (mm)

0.77 ± 0.03

0.79 ± 0.08

0.791 ± 0.09

0.916

Left ventricular end-diastolic dimension (mm)

4.18 ± 0.16^a

4.456 ± 0.17^b

4.22 ± 0.19^a

0.016

Left ventricular end-systolic dimension (mm)

2.78 ± 0.13^a

3.462 ± 0.49^b

3.09 ± 0.33^c

<0.001

Fractional shortening (%)

33.44 ± 0.85^a

22.82 ± 1.15^b

27.86 ± 1.61^c

<0.001

Left ventricular ejection fraction (%)

62.66 ± 1.43^a

46.04 ± 1.95^b

54.05 ± 5.41^c

<0.001