Skip to main content

Table 2 List of identified metabolites in umbilical cord plasma and in maternal peripheral blood

From: Metabolomic profiling in blood from umbilical cords of low birth weight newborns

  NEWBORNS p-value MOTHERS p-value Feto-maternal ratio p-value
  Control (n = 30) LBW (n = 20) C vs LBW M-Control (n = 30) M-LBW (n = 20) M-C vs M-LBW Control LBW Control vs LBW
Amino Acids and related          
 Proline 21.74 ± 9.80 13.00 ± 7.50 0.002 12.22 ± 0.92 12.10 ± 0.56 NS 1.73 ± 0.83 1.26 ± 0.62 0.023
 Free Choline 3.76 ± 0.17 2.58 ± 0.07 0.005 5.73 ± 0.79 5.80 ± 0.76 NS 0.56 ± 0.17 0.46 ± 0.17 0.040
 Citrulline 0.67 ± 0.02 0.84 ± 0.02 0.008 15.16 ± 1.09 15.34 ± 1.22 NS 0.04 ± 0.01 0.05 ± 0.02 0.022
 Glutamine 3.68 ± 0.17 2.59 ± 0.07 0.004 0.85 ± 0.06 0.85 ± 0.07 NS 3.68 ± 1.16 3.07 ± 0.81 0.024
 Alanine 9.49 ± 4.10 7.00 ± 2.20 0.008 0.90 ± 0.03 0.96 ± 0.20 NS 9.28 ± 3.29 7.66 ± 2.64 0.041
 Phenylalanine 1.07 ± 0.03 1.27 ± 0.03 0.018 9.78 ± 1.13 9.97 ± 0.96 NS 0.12 ± 0.03 0.13 ± 0.03 NS
Carbohydrates          
 Glucose 2.15 ± 0.98 1.59 ± 0.50 0.023 1.12 ± 0.08 1.10 ± 0.09 NS 1.65 ± 0.58 1.43 ± 0.42 NS
 Glycogen fragments 2.70 ± 1.11 2.01 ± 0.76 0.011 2.95 ± 0.33 2.82 ± 0.24 NS 0.81 ± 0.24 0.71 ± 0.27 NS
Lipids          
 LDL + VLDL enriched  spectral region 7.22 ± 1.25 7.60 ± 0.99 NS 5.01 ± 0. 50 4.96 ± 0.52 NS 1.52 ± 0.33 1.55 ± 0.23 NS
 PUFA N/D N/D -- 4.19 ± 0.49 4.38 ± 0.38 NS -- -- --
  1. The values are expressed as mean ± SD; p-value, statistical significance of the differences among groups; N/D, not detected; LBW, low birth weight. Mean metabolite abundance is indicated by arbitrary units of intensity (AUIx10-3).