Table 2 List of identified metabolites in umbilical cord plasma and in maternal peripheral blood
From: Metabolomic profiling in blood from umbilical cords of low birth weight newborns
NEWBORNS | p-value | MOTHERS | p-value | Feto-maternal ratio | p-value | ||||
|---|---|---|---|---|---|---|---|---|---|
Control (n = 30) | LBW (n = 20) | C vs LBW | M-Control (n = 30) | M-LBW (n = 20) | M-C vs M-LBW | Control | LBW | Control vs LBW | |
Amino Acids and related | |||||||||
Proline | 21.74 ± 9.80 | 13.00 ± 7.50 | 0.002 | 12.22 ± 0.92 | 12.10 ± 0.56 | NS | 1.73 ± 0.83 | 1.26 ± 0.62 | 0.023 |
Free Choline | 3.76 ± 0.17 | 2.58 ± 0.07 | 0.005 | 5.73 ± 0.79 | 5.80 ± 0.76 | NS | 0.56 ± 0.17 | 0.46 ± 0.17 | 0.040 |
Citrulline | 0.67 ± 0.02 | 0.84 ± 0.02 | 0.008 | 15.16 ± 1.09 | 15.34 ± 1.22 | NS | 0.04 ± 0.01 | 0.05 ± 0.02 | 0.022 |
Glutamine | 3.68 ± 0.17 | 2.59 ± 0.07 | 0.004 | 0.85 ± 0.06 | 0.85 ± 0.07 | NS | 3.68 ± 1.16 | 3.07 ± 0.81 | 0.024 |
Alanine | 9.49 ± 4.10 | 7.00 ± 2.20 | 0.008 | 0.90 ± 0.03 | 0.96 ± 0.20 | NS | 9.28 ± 3.29 | 7.66 ± 2.64 | 0.041 |
Phenylalanine | 1.07 ± 0.03 | 1.27 ± 0.03 | 0.018 | 9.78 ± 1.13 | 9.97 ± 0.96 | NS | 0.12 ± 0.03 | 0.13 ± 0.03 | NS |
Carbohydrates | |||||||||
Glucose | 2.15 ± 0.98 | 1.59 ± 0.50 | 0.023 | 1.12 ± 0.08 | 1.10 ± 0.09 | NS | 1.65 ± 0.58 | 1.43 ± 0.42 | NS |
Glycogen fragments | 2.70 ± 1.11 | 2.01 ± 0.76 | 0.011 | 2.95 ± 0.33 | 2.82 ± 0.24 | NS | 0.81 ± 0.24 | 0.71 ± 0.27 | NS |
Lipids | |||||||||
LDL + VLDL enriched spectral region | 7.22 ± 1.25 | 7.60 ± 0.99 | NS | 5.01 ± 0. 50 | 4.96 ± 0.52 | NS | 1.52 ± 0.33 | 1.55 ± 0.23 | NS |
PUFA | N/D | N/D | -- | 4.19 ± 0.49 | 4.38 ± 0.38 | NS | -- | -- | -- |