Figure 2

MMP-12 generated fragments of titin measured in a clinical cohort consisting of individuals with no diagnosed cardiac pathology and no coronary calcium. (CT-noCa) (n = 30), with high coronary calcium (CT-plusCa, n = 30), acute myocardial infarction (AMI, n = 30). A statistically significant difference between the groups was measured by one- way ANOVA (P < 0.05). The bar shows geometric mean value.