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Table 3 Correlations of clinical features of HCC patients with circulating Tregs and Bregs.

From: Perioperative dynamic alterations in peripheral regulatory T and B cells in patients with hepatocellular carcinoma

DESS evaluated Tregs Bregs
Clinicopathological Characteristic r P r P
Weight Loss -0.339 0.043* - -
HBV Infection History 0.360 0.031* - -
Leucocyte 0.363 0.029* - -
Hepatitis B e Antigen - - 0.527 0.030*
HBV DNA Copy number - - 0.532 0.028*
Ferritin -0.451 0.006** - -
Numbers of up-regulated tumor markers # -0.376 0.024* - -
Portal vein tumor thrombosis -.408* 0.014* - -
Hepatic vein invasion -.413* 0.012* - -
BCLC score -0.443 0.007** - -
TNM stage(AJCC) -0.347 0.038* - -
  1. (*, ** stands for P < 0.05, 0.01, respectively)
  2. # Tested tumor markers:α-fetoprotein; cancer antigen 125; cancer antigen 153; cancer antigen 199; Ferritin; Carcino-embryonic antigen; prostate specific antigen.
  3. HCC: Hepatocellular carcinoma; Tregs: Regulatory T cells; Bregs: Regulatory B cells; HBV: Hepatitis B virus; BCLC: Barcelona Clinic Liver Cancer Staging System; TNM (AJCC): Tumor-Node-Metastasis Staging System (American Joint Committee on Cancer).