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Table 3 Correlations of clinical features of HCC patients with circulating Tregs and Bregs.

From: Perioperative dynamic alterations in peripheral regulatory T and B cells in patients with hepatocellular carcinoma

DESS evaluated

Tregs

Bregs

Clinicopathological Characteristic

r

P

r

P

Weight Loss

-0.339

0.043*

-

-

HBV Infection History

0.360

0.031*

-

-

Leucocyte

0.363

0.029*

-

-

Hepatitis B e Antigen

-

-

0.527

0.030*

HBV DNA Copy number

-

-

0.532

0.028*

Ferritin

-0.451

0.006**

-

-

Numbers of up-regulated tumor markers #

-0.376

0.024*

-

-

Portal vein tumor thrombosis

-.408*

0.014*

-

-

Hepatic vein invasion

-.413*

0.012*

-

-

BCLC score

-0.443

0.007**

-

-

TNM stage(AJCC)

-0.347

0.038*

-

-

  1. (*, ** stands for P < 0.05, 0.01, respectively)
  2. # Tested tumor markers:α-fetoprotein; cancer antigen 125; cancer antigen 153; cancer antigen 199; Ferritin; Carcino-embryonic antigen; prostate specific antigen.
  3. HCC: Hepatocellular carcinoma; Tregs: Regulatory T cells; Bregs: Regulatory B cells; HBV: Hepatitis B virus; BCLC: Barcelona Clinic Liver Cancer Staging System; TNM (AJCC): Tumor-Node-Metastasis Staging System (American Joint Committee on Cancer).