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Figure 3 | Journal of Translational Medicine

Figure 3

From: Exosome removal as a therapeutic adjuvant in cancer

Figure 3

Schematic of Aethlon’s ADAPT™ device platform. This technology consists of plasmapheresis cartridges that allows blood cells to pass through the hollow fibers while serum components < 200 nm in size fit through the hollow fiber pores to interact with the affinity matrix. The matrices can be customized with one or more affinity substrates comprising monoclonal antibodies, lectins, aptamers or other affinity agents to specifically capture and remove tumor-derived exosomes and other soluble oncoproteins from the bloodstream using kidney dialysis or CRRT units.

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