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Table 2 Correlation between claspin expression and HR-HPV infection assessed by HC2 assay, stratified by histological diagnosis

From: Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix

Claspin expression n (%)

HR-HPV n (%)

WNL n = 9

CIN1 n = 19

CIN2 n = 21

CIN3 n = 16

SCC n = 15

Negative/Low33 (41.2)

Negative 10 (30.3)

5

5

\

\

\

Positive 23 (69.7)

4

11

5

2

1

Moderate/High47 (58.8)

Negative 1 (2.2)

\

1

\

\

\

 

Positive 46 (97.8)

\

2

16

14

14

  1. p(χ2) <0.0001.
  2. HR-HPV, High Risk Human Papillomavirus; WNL, Within Normal Limit; CIN, Cervical Intraepithelial Neoplasia; SCC, Squamous Cell Carcinoma.