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Table 2 Correlation between claspin expression and HR-HPV infection assessed by HC2 assay, stratified by histological diagnosis

From: Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix

Claspin expression n (%) HR-HPV n (%) WNL n = 9 CIN1 n = 19 CIN2 n = 21 CIN3 n = 16 SCC n = 15
Negative/Low33 (41.2) Negative 10 (30.3) 5 5 \ \ \
Positive 23 (69.7) 4 11 5 2 1
Moderate/High47 (58.8) Negative 1 (2.2) \ 1 \ \ \
  Positive 46 (97.8) \ 2 16 14 14
  1. p(χ2) <0.0001.
  2. HR-HPV, High Risk Human Papillomavirus; WNL, Within Normal Limit; CIN, Cervical Intraepithelial Neoplasia; SCC, Squamous Cell Carcinoma.