Figure 1
From: Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix
Western blot analysis of cell lines. Western blot analysis with a claspin specific antibody performed on NHEK (lane 1), HK-168 (lane 2), SiHa (lane 3), CaSki (lane 4), HeLa cell lines (lane 5). Actin was used as an internal control for sample loading. Because claspin activity is regulated by phosphorylation, the high molecular weight band might correspond to a phosphorylated form while the low molecular weight band might be due to protein degradation.